Synthesis and evaluation of heterocycle structures as potential inhibitors of Mycobacterium tuberculosis UGM.

This study made it possible to highlight an "oxazepino-indole" structure as a new inhibitor of UGM and of M. tuberculosis growth in vitro.
PMID: 32546296 [PubMed - in process]

Source: Bioorganic and Medicinal Chemistry - June 18, 2020 Category: Chemistry Authors: Maaliki C, Fu J, Villaume S, Viljoen A, Raynaud C, Hammoud S, Thibonnet J, Kremer L, Vincent SP, Thiery E Tags: Bioorg Med Chem Source Type: research