Endoscopic tattooing for colorectal lesions: impact on quality of care and patient outcomes.

CONCLUSIONS: Our study highlights the lack of uniformity of tattoo practice among endoscopists. Despite the National Bowel Cancer Screening Programme guidelines, a significant proportion of colorectal lesions are still not tattooed during their first endoscopy. Some patients had to have repeat endoscopy just for the purpose of tattooing. Active involvement and participation of all endoscopists in the colorectal and the complex polyp multidisciplinary teams may help to improve the tattoo service. PMID: 32538104 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Tags: Ann R Coll Surg Engl Source Type: research

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Colorectal cancer (CRC) is the third most common cancer in both males and females in the UK, giving rise to approximately 40,000 new cancer cases per year. It arises from polyps as part of the adenoma-carcinoma sequence. Early detection can aid treatment and improve outcomes. Faecal immunochemical tests (FIT) and direct imaging using colonoscopy/sigmoidoscopy has been shown to be advantageous in the detection of polyps and earlier cancer. We review the evidence and provide summaries of current strategies as well as future potential developments.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Intestinal surgery – I Source Type: research
Colorectal cancer is a preventable disease.1 Bowel cancer screening whether via fecal immunochemical testing, flexible sigmoidoscopy, or primary colonoscopy, decreases the risk of future colorectal cancer significantly, and colonoscopy is the final common pathway in screening to remove polyps and prevent cancer1,2; however, despite this effectiveness, it has also become evident that colonoscopy is not perfect and cancers occur after a “clear” colonoscopy at a rate of between 2.5% and 8.7% of the total cancers diagnosed, depending on the method used to calculate and the population.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Editorial Source Type: research
ConclusionsThe prevalence rates for neoplasms, advanced neoplasms, and CRC in our current study were statistically significantly higher compared with those seen in average-risk populations. This supports the importance of more intensive screening for this subpopulation in preventing colorectal cancers, as well as pre-and early-cancerous neoplasms.
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research
Sir — We thank Laverty et al. for their correspondence and congratulations in response to our work.1 Please accept our apologies for the discrepancy in polyp categorisation. The revised polyp data in line with National Bowel Cancer Screening programme, the European Society of Gastrointestinal and Abd ominal Radiology (ESGAR) consensus guidelines2 and other published studies is as follows3,4: the total polyp detection rate was 13.5% (241 polyps) in 170 patients; 153 (63.5%) polyps were ≥10 mm in size compared to 88 (36.5%) measuring between 6–9 mm.
Source: Clinical Radiology - Category: Radiology Authors: Tags: Correspondence Source Type: research
This study was carried out in accordance with approval of the Melbourne Health and Walter and Eliza Hall Institute of Medical Research's Human Research Ethics Committee (approval number: 2013.081). All subjects gave written informed consent for participation and publication. Results and Discussion TGF-β signaling in NK cells is associated with: phosphorylation in SMAD2 and 3, inhibition of IL-15-induced metabolism/proliferation, simultaneous downregulation of CD44, CD49e, and Eomes, and upregulation of CD16 and CD49a expression (7, 10). SMAD family member 4 (SMAD4) belongs to the SMAD family of transcription...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Epidemiologist whose research led to a breakthrough in bowel cancer screening programmes worldwide“Breakthrough” is an overused word when applied to medical advances. But in the case of the2010 trial of a new screening test for bowel cancer led by Wendy Atkin, professor of gastrointestinal epidemiology atImperial College London, who has died of acute myeloid leukaemia aged 71, it is fully deserved. Its impact will be felt by millions. The trial was the first in the world to show that bowel cancer – the second biggest cancer killer in the UK – could be prevented with a simple, five-minute test.The ex...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Cancer research Health Medical research Science Source Type: news
Publication date: Available online 19 November 2018Source: The LancetAuthor(s): Mark A Hull, Kirsty Sprange, Trish Hepburn, Wei Tan, Aisha Shafayat, Colin J Rees, Gayle Clifford, Richard F Logan, Paul M Loadman, Elizabeth A Williams, Diane Whitham, Alan A Montgomery, seAFOod Collaborative GroupSummaryBackgroundThe omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) and aspirin both have proof of concept for colorectal cancer chemoprevention, aligned with an excellent safety profile. Therefore, we aimed to test the efficacy of EPA and aspirin, alone and in combination and compared with a placebo, in individuals w...
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionInvesting in public health strategies to increase adherence to appropriate CRC screening will save lives and deliver high value for money.
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Endosc Int Open 2018; 06: E872-E877 DOI: 10.1055/a-0591-9308 Background and study aims UK Bowel Cancer Screening flexible sigmoidoscopy (BowelScope) currently offers patients aged 55 a one-off flexible sigmoidoscopy for adenoma clearance to decrease colorectal cancer incidence by interrupting the adenoma-carcinoma sequence. Recent evidence has shown maximum benefit in increasing adenoma detection rate (ADR) using the Endocuff Vision device in the left side of the colon and in screening patients. Currently, ADR is low and shows unacceptable variation in BowelScope. ADR is a quality indicator in screening sigmoidosco...
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Determining adenoma detection rate (ADR) is important to ensure quality colonoscopy. The minimum standard of 25% in screening patients aged>50 years is recommended by professional organisations. Despite reasonable uptake of the National Bowel Cancer Screening Program, most patients in Australian endoscopy units are symptomatic (diagnostic) or have a personal history of polyps (surveillance). While patients with a 10 family history of colorectal cancer
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Saturday abstract Source Type: research
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