New Inhibitors for the BPTF Bromodomain Enabled by Structural Biology and Biophysical Assay Development

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00506A, PaperPeter D. Ycas, Huda Zahid, Alice Chan, Noelle Olson, Jorden A. Johnson, Siva Talluri, Ernst Sch önbrunn, William Pomerantz Bromodomain-containing proteins regulate transcription through protein-protein interactions with chromatin and serve as scaffolding proteins for recruiting essential members of the transcriptional machinery. One such protein is the bromodomain and PHD-containing... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research