Identifying the epileptogenic zone by four non-invasive imaging techniques versus stereo-EEG in MRI-negative pre-surgery epilepsy patients.

CONCLUSIONS: The study highlights the accuracy of a combination of functional imaging techniques in the identification of EZ in MRI negative focal epilepsy. The best diagnostic yield was obtained if the combination of PET, MEG (or HR-EEG as alternative), EEG-fMRI were considered together.
SIGNIFICANCE: The functional imaging techniques may improve the presurgical workup of MRI negative focal epilepsy, if epileptogenic zone involves more than one lobe.
PMID: 32544836 [PubMed - as supplied by publisher]

Source: Clinical Neurophysiology - June 2, 2020 Category: Neurology Authors: Rossi Sebastiano D, Tassi L, Duran D, Visani E, Gozzo F, Cardinale F, Nobili L, Del Sole A, Rubino A, Dotta S, Schiaffi E, Garbelli R, Franceschetti S, Spreafico R, Panzica F Tags: Clin Neurophysiol Source Type: research