Metformin inhibits intracranial aneurysm formation and progression by regulating vascular smooth muscle cell phenotype switching via the AMPK/ACC pathway

The regulation of vascular smooth muscle cell (VSMC) phenotype plays an important role in intracranial aneurysm (IA) formation and progression. However, the underlying mechanism remains unclear. Metformin is a...

Source: Journal of Neuroinflammation - June 16, 2020 Category: Neurology Authors: Sichen Li, Yuan Shi, Peixi Liu, Yaying Song, Yingjun Liu, Lingwen Ying, Kai Quan, Guo Yu, Zhiyuan Fan and Wei Zhu Tags: Research Source Type: research