Coagulation factor XIII activity predicts left ventricular remodelling after acute myocardial infarction

ConclusionsFXIII activity after MI is highly dynamic, exhibiting a significant decline in the early healing period, with reconstitution 6  months later. Depressed FXIIIa early after MI predicted a greater size of MI and lower left ventricular ejection fraction after 1 year. The clinical relevance of these findings awaits to be tested in a randomized trial.

Source: ESC Heart Failure - June 16, 2020 Category: Cardiology Authors: Anna Frey, Tobias Gassenmaier, Ulrich Hofmann, Dominik Schmitt, Georg Fette, Almuth Marx, Sabine Herterich, Val érie Boivin‐Jahns, Georg Ertl, Thorsten Bley, Stefan Frantz, Roland Jahns, Stefan Störk Tags: Original Research Article Source Type: research