Effects of transcranial direct current stimulation of left and right inferior frontal gyrus on creative divergent thinking are moderated by changes in inhibition control

AbstractDivergent thinking (DT) as one component of creativity is the ability to search for multiple solutions to a single problem and is reliably tested with the Alternative Uses Task (AUT). DT depends on activity in the inferior frontal gyrus (IFG), a prefrontal region that has also been associated with inhibitory control (IC). Experimentally manipulating IC through transcranial direct current stimulation (tDCS) led to alterations in DT. Here, we aimed at further examining such potential mediating effects of IC on DT (measured as flexibility, fluency, and originality in the AUT) by modulating IC tDCS. Participants received either cathodal tDCS (c-tDCS) of the left IFG coupled with anodal tDCS (a-tDCS) of the right IFG (L −R + ;N = 19), or the opposite treatment (L + R−;N = 21). We hypothesized that L + R− stimulation would enhance IC assessed with the Go NoGo task (GNGT), and that facilitated IC would result in lower creativity scores. The reversed stimulation arrangement (i.e., L− R +) should result in higher creativity scores. We found that tDCS on ly affected the originality component of the AUT but not flexibility or fluency. We also found no effects on IC, and thus, the mediation effect of IC could not be confirmed. However, we observed a moderation effect: inhibition of left and facilitation of right IFG (L−R +) resulted in enhanced fl exibility and originality scores, only when IC performance was also improved. We conclude that indu...

Source: Anatomy and Embryology - June 16, 2020 Category: Anatomy Source Type: research