Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression
Accumulating evidence implicates dysregulation of hippocampal synaptic plasticity in the pathophysiology of depression. However, the effects of ketamine on synaptic plasticity and their contribution to its mec...
Source: Molecular Brain - Category: Neuroscience Authors: Lily R. Aleksandrova, Yu Tian Wang and Anthony G. Phillips Tags: Research Source Type: research