Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escape Chlamydia trachomatis variants

Four new variants of Chlamydia trachomatis (nvCTs), detected in several countries, cause false-negative or equivocal results using the Aptima Combo 2 assay (AC2; Hologic). We evaluated the clinical sensitivity an...

Source: BMC Infectious Diseases - June 16, 2020 Category: Infectious Diseases Authors: Magnus Unemo, Marit Hansen, Ronza Hadad, Mirja Puolakkainen, Henrik Westh, Kaisu Rantakokko-Jalava, Carina Thilesen, Michelle J. Cole, Iryna Boiko, Pham T. Lan, Daniel Golparian, Shin Ito and Martin Sundqvist Tags: Research article Source Type: research