COQ8B nephropathy: Early detection and optimal treatment

ConclusionsCOQ8B mutations are one of the most common causes of adolescent ‐onset proteinuria and/or CKD of unknown etiology in the Chinese children. Early detection of COQ8B nephropathy following CoQ10 supplementation combined with ACE inhibitor could slow the progression of renal dysfunction. Renal transplantation in patients withCOQ8B nephropathy showed no recurrence of proteinuria.

Source: Molecular Genetics & Genomic Medicine - June 15, 2020 Category: Genetics & Stem Cells Authors: Xiaoxiang Song, Xiaoyan Fang, Xiaoshan Tang, Qi Cao, Yihui Zhai, Jing Chen, Jialu Liu, Zhiqing Zhang, Tianchao Xiang, Yanyan Qian, Bingbing Wu, Huijun Wang, Wenhao Zhou, Cuihua Liu, Qian Shen, Hong Xu, Jia Rao Tags: ORIGINAL ARTICLE Source Type: research