Progress in Primary Aldosteronism 2019: New Players on the Block?
Horm Metab Res 2020; 52: 345-346 DOI: 10.1055/a-1156-9926Primary aldosteronism (PA) is characterized by hypertension caused by inappropriately
high adrenal aldosterone secretion, consecutively low plasma renin, and an elevated
aldosterone to renin ratio. It is nowadays the universally accepted main cause of
endocrine hypertension. According to the most recent epidemiological data, PA is
present in 5.8% of unselected hypertensives in primary care,
6–12% of hypertensives treated in hypertension centers, and up to
30% in subjects with resistant hypertension 1. Despite this high prevalence, a recent survey demonstrated that
screening for PA is not universally followed. Renin and aldosterone measurements,
the basis for PA screening, are currently performed by only 7% of general
practitioners in Italy and 8% in Germany 2. Accordingly, the prevalence of PA was low with 1% among
hypertensives in Italy and 2% in Germany. In a retrospective cohort study of
4660 patients with resistant hypertension in California the screening rate for PA
was 2.1% 3. Based on these data, it
is clear that we still miss the majority of PA cases, despite advances in diagnosis
and therapy. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Reincke, Martin Beuschlein, Felix Williams, Tracy Ann Tags: Editorial Source Type: research
More News: Endocrinology | Epidemiology | Germany Health | Hormones | Hypertension | Italy Health | Primary Care | Study