Regulation of Hox and ParaHox Genes by Perfluorochemicals in Mouse Liver.

In conclusion, PFCs induced mRNA expression of several Hox genes such as Hoxb7, c5 and d10, mostly through the activation of PPARα and/or Nrf2 signaling.
PMID: 32534105 [PubMed - as supplied by publisher]

Source: Toxicology - June 9, 2020 Category: Toxicology Authors: Zhang Y, Le Y, Bu P, Cheng X Tags: Toxicology Source Type: research