What Causes Pyogenic Granulomas?

Discussion Pyogenic granuloma (PG) is a benign, vascular lesion of the skin. PGs are red, small, often pedunculated nodules that can rapidly increase in size (up to 1-2 cm). They also can often ulcerate and bleed. They frequently occur on the head and neck, with back and chest being the next most common locations but can occur in other locations. They usually are solitary and do not regress. They are seen in children (mean age 6.7 years), young adults and pregnant women (5%). Treatment is electrocautery or excision. Learning Point PG’s cause is not fully understood. A gene has recently been identified with PG suggesting it is a benign neoplasm and simply caused by a reactive etiology. PG is usually an acquired lesion that occurs after skin trauma, insect bites, infection, eczema, burns, oral retinoid therapy, and underlying vascular lesions. Acquired PG can be simple to diagnose if the history and physical examination are more classic or with monitoring over time to evaluate the lesion. Deep-seated or subcutaneous PG is not common but does occur. Congenital PG is rare and often affects the mucosa. Multiple congenital PG is even less common. It may look like infantile hemangiomas or other vascular tumors. Even on biopsy, congenital or deep-seated PG can be difficult to diagnose. Questions for Further Discussion 1. What are common congenital vascular cutaneous lesions? 2. What are common acquired vascular lesions? 3. What cutaneous zoonoses might be considered for c...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news