Hepatitis B virus X protein boosts hepatocellular carcinoma progression by downregulating microRNA-137.

CONCLUSION: Overexpression of miR-137 blocks HCC cell proliferation in HBx-siRNA-treated MHCC97H cells by targeting Notch1. This study may offer novel target for HCC treatment.
PMID: 32527447 [PubMed - in process]

Source: Pathology, Research and Practice - May 31, 2020 Category: Pathology Authors: Gao Y, Gu J, Wang Y, Fu D, Zhang W, Zheng G, Wang X Tags: Pathol Res Pract Source Type: research