Nuclear expression of BAP-1 in transvitreal incisional biopsies and subsequent enucleation of eyes with posterior choroidal melanoma.

CONCLUSION: Loss of nuclear BAP-1 expression occurred in a large proportion of the small tumours included in this study. BAP-1 immunoreactivity in transvitreal incisional biopsies of choroidal melanoma is substantially concordant with immunoreactivity in enucleated specimens and identifies patients with poor metastasis-free survival.
PMID: 32522791 [PubMed - as supplied by publisher]

Source: The British Journal of Ophthalmology - June 9, 2020 Category: Opthalmology Authors: Herrspiegel C, Kvanta A, Lardner E, Ramsköld Cabaca L, Wells J, Bartuma K, Seregard S, Stålhammar G Tags: Br J Ophthalmol Source Type: research