Pharmacovigilance Assessment of Cardiac Implications of Nicotine Replacement Therapy Among Smokers.

CONCLUSION: Our study findings showed lower cardiac disorder risk with NRT group compared to non-NRT (varenicline and bupropion) group. While the study was not aimed to undermine either using NRT or non-NRT for smoking cessation therapy to prevent smoking illness, the study results offer informed findings that could potentially improve current smoking cessation management using NRT intervention among smokers and enhance smokers' health outcome. Despite the negative signal detection of cardiac disorder risk with NRT as compared to non-NRT in final findings, we still recommend further research on causal relationship between NRT and nonNRT and cardiac disorder risk. PMID: 32525783 [PubMed - as supplied by publisher]
Source: Current Drug Safety - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Saf Source Type: research