Apathy is associated with white matter network disruption and specific cognitive deficits in Parkinson's disease.

CONCLUSIONS: Our results suggest compromised neural integration and reduced structural connectivity in aPD. Apathy, depression, and motor severity showed distinct impacts on different cognitive functions with apathy being the most influential determinant of cognition in PD.
PMID: 32524922 [PubMed - as supplied by publisher]

Source: Psychological Medicine - June 10, 2020 Category: Psychiatry Authors: Wen MC, Thiery A, Tseng WI, Kok T, Xu Z, Chua ST, Tan LCS Tags: Psychol Med Source Type: research