Human Norovirus Replication in Temperature-Optimized MDCK Cells by Forkhead Box O1 Inhibition.

In conclusion, temperature-optimized MDCK cells can be used as a convenient culture model for HuNoV replication by inhibiting FOXO1, providing adaptability to different genotypes.
PMID: 32522961 [PubMed - as supplied by publisher]

Source: Journal of Microbiology and Biotechnology - June 7, 2020 Category: Biotechnology Authors: Jeong EH, Cho SY, Vaidya B, Ha SH, Jun S, Ro HJ, Lee Y, Lee J, Kwon J, Kim D Tags: J Microbiol Biotechnol Source Type: research