The impact of regional astrocyte interferon- γ signaling during chronic autoimmunity: a novel role for the immunoproteasome

In early autoimmune neuroinflammation, interferon (IFN) γ and its upregulation of the immunoproteasome (iP) is pathologic. However, during chronic multiple sclerosis (MS), IFNγ has protective properties. Althou...

Source: Journal of Neuroinflammation - June 12, 2020 Category: Neurology Authors: Brandon C. Smith, Maksim Sinyuk, Julius E. Jenkins III, Morgan W. Psenicka and Jessica L. Williams Tags: Research Source Type: research