Diagnostic accuracy of intrathecal kappa free light chains compared with OCBs in MS

Conclusion All evaluated KFLC metrics have excellent accuracy, and both KFLC intrathecal fraction and CSF KFLC/CSF albumin are at least as good as OCB in separating patients with MS from a control group. Classification of evidence This study provides Class III evidence that CSF KFLC accurately distinguishes patients with MS from healthy controls.
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: Tags: Diagnostic test assessment, Multiple sclerosis Article Source Type: research