Repurposing the Dihydropyridine Calcium Channel Inhibitor Nicardipine as a Na v 1.8 Inhibitor In Vivo for Pitt Hopkins Syndrome

ConclusionsThesein vivo results in the well characterized Tcf4( ± ) PTHS mice may suggest the potential to test this already approved drug further in a clinical study with PTHS patients or suggest the potential for use off label under compassionate use with their physician.
Source: Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research