Dowling & #8211;Degos disease with follicular involvement associated with hidradenitis suppurativa: A manifestation of follicular occlusion phenomenon ?

We report a case of DDD with follicular involvement and hidradenitis suppurativa (HS) which is a rare association and can be explained on the basis of single underlying defect in follicular epithelial proliferation. DDD-HS has been shown to result from mutations in PSENEN, encoding a critical component of the γ-secretase complex.

Source: Indian Journal of Dermatology - June 10, 2020 Category: Dermatology Authors: Bhagyashree Babanrao Supekar Kinjal Deepak Rambhia Rajesh Pratap Singh Jayesh Ishwardas Mukhi Source Type: research