Pharmacotherapy for borderline personality disorder

In this podcast, Dr Kamran Ahmed talks to Professor Klaus Lieb about the Cochrane review conducted by his team on trials of pharmacological treatments for borderline personality disorder (Lieb et al, 2010). The findings of the review and their implications are discussed.
Source: Raj Persaud talks to... - Category: Psychiatry Tags: Science & Medicine Source Type: podcasts

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ConclusionIn conclusion, our findings should encourage clinical practitioners to address trust deficits towards close others, as well as omniscient negative memory retrieval and interpretation biases which might influence current trust behavior.
Source: Borderline Personality Disorder and Emotion Dysregulation - Category: Psychiatry Source Type: research
Purpose of review Borderline personality disorder (BPD) attracts significant attention from clinicians and researchers alike. Despite increased recognition and willingness to diagnose BPD, most effective treatment approaches remain inaccessible to most. We consider recent developments in the diagnosis and treatment of BPD. Recent findings A literature search of EMBASE and PsychINFO, using the search terms ‘borderline personality disorder,’ ‘diagnosis’ and ‘treatment’ for publications since October 2018, yielded over 300 articles and reviews. The literature highlights the increasing ...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: PSYCHIATRY, MEDICINE AND THE BEHAVIOURAL SCIENCES: Edited by Mohan Isaac and Igor Filipcic Source Type: research
CONCLUSIONS: The findings suggest that the measurement of inter-trial variability in brain activity may be more valuable than the average level for revealing neurophysiological differences associated with impulsivity and personality risk factors for dependence. EEG measures may be particularly valuable in this context because they offer superior temporal resolution and signal-to-noise characteristics. PMID: 32735715 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
Authors: Lorettu L, Pes GM, Dore MP, Milia P, Nivoli A Abstract The relationship between eating disorders and diabetes is complex in terms of both reciprocity and comorbidity. In some cases, patients with eating disorders and diabetes develop 'purging' behaviours through the use of insulin as a bodyweight control tool, with serious physical complications that can compared to those of untreated diabetes (diabulimia). The clinical cases presented have in common the distorted use of insulin: one patient failed to take the required amounts of insulin, incurring hyperglycaemia, while the other overused it, incurring hyp...
Source: Rivista di Psichiatria - Category: Psychiatry Tags: Riv Psichiatr Source Type: research
Publication date: Available online 29 July 2020Source: Journal of Psychiatric ResearchAuthor(s): Jillian H. Broadbear, Jeremy Dwyer, Lyndal Bugeja, Sathya Rao
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
ConclusionsIn light of our findings, we believe that the current legislation and practice of EAS for people with personality disorders is based on an inadequate understanding of underlying psychopathology and a lack of awareness about the contemporary treatment literature. Moreover, we assert that this practice neglects the individual ’s potential for having a life worth living.
Source: Borderline Personality Disorder and Emotion Dysregulation - Category: Psychiatry Source Type: research
CONCLUSIONS: Our longitudinal study of a well-characterized clinical sample found more evidence for stress generation than for stress-induced decompensation in BPD. Stress generation in BPD is driven by externalizing dimensions: antagonism and disinhibition. These results highlight the utility of empirically derived dimensions for parsing heterogeneity present in BPD, leading to improvements in diagnostic evaluation, clinical prediction, and individualized approaches to treatment planning. PMID: 32713398 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Publication date: Available online 26 July 2020Source: Journal of Psychiatric ResearchAuthor(s): Diana Galletta, Califano Annamaria Immacolata, Fausta Micanti, Carmen Santoriello, Andrea de Bartolomeis
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Vafidemstat may reduce agitation and aggression in autism, ADHD, and borderline personality disorder. It's also the first psychiatric drug with an epigenetic mode of action, investigators say.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Psychiatry News Source Type: news
I am a 4th year DO student who is interested in psychiatry with several red flags--LOA for 6 month and low board scores (no failures in boards/courses/clerkship). FYI, I took a LOA for 6 months due to personal issues (family illness/ financial difficulties/relationship problem with a partner who has borderline personality disorder). I had been dealing with these issues for more than three years before I finally decided to take a LOA before breaking down. My grades started going down... Please advise.. Applying to residency with several red flags.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: General Residency Issues Source Type: forums
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