Protein translocation into the ERGIC: an upstream event of secretory autophagy.

Protein translocation into the ERGIC: an upstream event of secretory autophagy.
Autophagy. 2020 Jun 10;:1-3
Authors: Liu L, Zhang M, Ge L
Abstract
Macroautophagy/autophagy was recently shown to regulate unconventional protein secretion through a process called secretory autophagy. How the secretory cargo selectively enters into the secretory autophagosome has been a central question. Our recent studies indicate that cargo translocation into the ER-Golgi intermediate compartment, a compartment contributing membranes to the forming autophagosome, acts as a mechanism for secretory cargo entry into the vesicle and may be an early step for secretory autophagy.
PMID: 32521187 [PubMed - as supplied by publisher]

Source: Autophagy - June 9, 2020 Category: Cytology Authors: Liu L, Zhang M, Ge L Tags: Autophagy Source Type: research