Clinicopathological factors associated with tumor-infiltrating lymphocyte reactivity in breast cancer

ConclusionTILs from approximately half the TNBC cases with NAC showed reactivity against autologous cancer cells. The proportion of PD-1+ T cells was higher in the reactive group. Adoptive TIL therapy combined with PD-1 inhibitors might be promising for TNBC patients with residual tumors after NAC.

http://link.springer.com/10.1007/s00262-020-02633-5

Source: Cancer Immunology, Immunotherapy - June 10, 2020 Category: Cancer & Oncology Source Type: research