In Vitro Activities of Eravacycline and Other Antimicrobial Agents Against Human Mycoplasmas and Ureaplasmas.

In Vitro Activities of Eravacycline and Other Antimicrobial Agents Against Human Mycoplasmas and Ureaplasmas. Antimicrob Agents Chemother. 2020 Jun 08;: Authors: Waites KB, Crabb DM, Xiao L, Duffy LB, Leal SM Abstract We performed in vitro susceptibility testing for eravacycline in comparison to 4 other antimicrobials against 10 Mycoplasma genitalium, 40 M. hominis, 44 M. pneumoniae, 20 Ureaplasma parvum, and 20 U. urealyticum All eravacycline MICs were ≤ 0.25 μg/ml except for one isolate of M. genitalium for which the MIC was 2 μg/ml. Eravacycline was markedly more potent than tetracycline, azithromycin, moxifloxacin, and clindamycin against all isolates tested, which included 37 macrolide, tetracycline, and/or fluoroquinolone-resistant organisms. PMID: 32513794 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research