Exploring the biotransformation of N ‐(2‐hydroxyphenyl)‐2‐propylpentanamide (an aryl valproic acid derivative) by CYP2C11, using in silico predictions and in vitro studies

ConclusionTherefore, rat liver CYP2C11 isoform is able to metabolize HO ‐AAVPA.

Source: Journal of Pharmacy and Pharmacology - June 7, 2020 Category: Drugs & Pharmacology Authors: Jessica Elena Mendieta ‐Wejebe, Arianna Silva‐Trujillo, Martiniano Bello, Humberto L. Mendoza‐Figueroa, Norma Lizeth Galindo‐Alvarez, Arnulfo Albores, Feliciano Tamay‐Cach, Martha Cecilia Rosales‐Hernández, Aurelio Romero‐Castro, J Tags: Research Paper Source Type: research