Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk.

Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk.
Trends Microbiol. 2020 Jun 04;:
Authors: Dubinsky V, Dotan I, Gophna U
Abstract
Colibactin is a genotoxic molecule, produced primarily by Escherichia coli. Colibactin causes DNA damage that may lead to colorectal cancer. Here we review recent advances in the study of colibactin and propose a focus on patients with inflammatory bowel diseases (IBD) who have higher levels of colibactin-producing bacteria in their intestines.
PMID: 32507544 [PubMed - as supplied by publisher]

Source: Trends in Microbiology - June 3, 2020 Category: Microbiology Authors: Dubinsky V, Dotan I, Gophna U Tags: Trends Microbiol Source Type: research