In Vivo Evaluation of Indium-111 –Labeled 800CW as a Necrosis-Avid Contrast Agent

Conclusions[111In]In-DOTA-PEG4-800CW can be used to image tumor necrosisin vitro andin vivo. Further research will elucidate the application of [111In]In-DOTA-PEG4-800CW or other radiolabeled hydrophilic cyanines for the detection of necrosis caused by chemotherapy or other anti-cancer therapies. This can provide valuable prognostic information in treatment of solid tumors.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research