Immunosuppressive tumor microenvironment in occupational cholangiocarcinoma: Supportive evidence for the efficacy of immune checkpoint inhibitor therapy

ConclusionsThe tumor microenvironment of occupational CCA had features of immunosuppression, and the occurrence of T ‐cell dysfunction or exhaustion was suggested. The results provide supportive evidence for the efficacy of immune checkpoint inhibitor therapy for this disease.

Source: Journal of Hepato-Biliary-Pancreatic Sciences - June 6, 2020 Category: Gastroenterology Authors: Yasunori Sato, Shogo Tanaka, Masahiko Kinoshita, Shigekazu Takemura, Hiroji Shinkawa, Takashi Kokudo, Kiyoshi Hasegawa, Hiromu Tanaka, Hidero Yoshimoto, Akira Mori, Minako Yamamura, Motoko Sasaki, Kenichi Harada, Shoji Kubo Tags: ORIGINAL ARTICLE Source Type: research