Towards an understanding of women's brain aging: the immunology of pregnancy and menopause.

Towards an understanding of women's brain aging: the immunology of pregnancy and menopause. Front Neuroendocrinol. 2020 Jun 03;:100850 Authors: Barth C, de Lange AG Abstract Women are at significantly greater risk of developing Alzheimer's disease and show higher prevalence of autoimmune conditions relative to men. Women's brain health is historically understudied, and little is therefore known about the mechanisms underlying epidemiological sex differences in neurodegenerative diseases, and how female-specific factors may influence women's brain health across the lifespan. In this review, we summarize recent studies on the immunology of pregnancy and menopause, emphasizing that these major immunological and hormonal transition phases may play a critical part in women's brain aging trajectories. PMID: 32504632 [PubMed - as supplied by publisher]
Source: Frontiers in Neuroendocrinology - Category: Endocrinology Authors: Tags: Front Neuroendocrinol Source Type: research