Antidepressant Effect and Modulation of the Redox System Mediated by Tannic Acid on Lipopolysaccharide-Induced Depressive and Inflammatory Changes in Mice.

In conclusion, TA shows many neuroprotective properties, with demonstrated antioxidant, anti-inflammatory and antidepressant effects in this animal model of acute depressive-like behavior. Therefore, this compound could provide an alternative therapeutic approach for the treatment of depression.
PMID: 32500408 [PubMed - as supplied by publisher]

Source: Neurochemical Research - June 4, 2020 Category: Neuroscience Authors: Luduvico KP, Spohr L, Soares MSP, Teixeira FC, de Farias AS, Bona NP, Pedra NS, de Oliveira Campello Felix A, Spanevello RM, Stefanello FM Tags: Neurochem Res Source Type: research