Cardiac Resynchronization Therapy for Improving Non-Uniform Thickening of Left Ventricular Wall: Assessment by Quantitative Gated Myocardial Perfusion SPECT.

In conclusion, CRT improved non-uniformity of wall thickening between the LV septal and lateral regions evaluated using QGS, which is predictive of better prognosis in the chronic phase after CRT. PMID: 32493869 [PubMed - in process]
Source: The Tohoku Journal of Experimental Medicine - Category: Research Authors: Tags: Tohoku J Exp Med Source Type: research

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This article seeks to review the latest evidence with a view to explaining possible pharmacotherapies for the cardiovascular complications of COVID-19 including acute coronary syndrome, heart failure, myocarditis, arrhythmias, and venous thromboembolism, as well as possible interactions between these medications and those currently administered (or under evaluation) in the treatment of COVID-19.
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research
Conclusion: The risk of severe maternal cardiac complications during pregnancy in women with congenital heart disease is low. In this largest analysis to date with a focus on parity in 307 women, the risk classification predicts the maternal outcome more than parity per se. If the first pregnancy is uneventful, the OR is 5.5 for an uneventful second pregnancy if CARPREG I and mWHO scores remain unchanged.Cardiology
Source: Cardiology - Category: Cardiology Source Type: research
In this study, we investigated the effects of how HF-induced atrial cellular electrophysiological (with prolonged AP duration) and tissue stru ctural (reduced cell-to-cell coupling caused by atrial fibrosis) remodelling can have an effect on the generation of atrial AP alternans and their conduction at the cellular and one-dimensional (1D) tissue levels. Simulation results showed that HF-induced atrial electrical remodelling prolonged AP d uration, which was accompanied by an increased sarcoplasmic reticulum (SR) Ca2+ content and Ca2+ transient amplitude. Further analysis demonstrated that HF-induced atrial electrical remo...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
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Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: EDITORIAL ‐ INVITED Source Type: research
Authors: Gunawardene MA, Hartmann J, Jularic M, Eickholt C, Gessler N, Willems S Abstract Atrial fibrillation (AF) is the most frequent persistent cardiac arrhythmia and is associated with an increased mortality. Therefore, an effective differential treatment of patients is mandatory. After a risk stratification oral anticoagulation (OAC) should be initiated depending on the individual stroke risk of each patient. Alternatively, in the presence of contraindications for OAC and an increased risk for bleeding and/or stroke, the implantation of a left atrial appendage closure device can be considered. Symptomatic pati...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
ESC Heart Failure, EarlyView.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Editorial Source Type: research
It is clear that existing cardiovascular disease is a major risk factor for COVID-19 and related adverse outcomes. In addition to acute respiratory syndrome, a large cohort also develop myocardial and/or vascular dysfunction, in part from inflammation and renin angiotensin system activation with increased sympathetic outflow, cardiac arrhythmias, ischemia, heart failure, and thromboembolic complications that portend poor COVID-19 outcomes.We summarize here recent information for hospitalists/internists on the front-line of this pandemic regarding its cardiovascular impacts and management and need for cardiovascular consultation.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Review Source Type: research
We describe the various pharmacological and non-pharmacological strategies for AF management with a peek at some futuristic approaches. While each one of these variables could lend themselves for a separate review, we attempted to provide an overview of the most critical predictors of AF outcomes to equip the readers with the latest know-how of the management of AF.
Source: Current Cardiovascular Risk Reports - Category: Cardiology Source Type: research
AbstractFabry disease (FD) is an X ‐linked lysosomal storage disorder caused by pathogenic variants in the α‐galactosidase A gene (GLA) that leads to reduced or undetectable α‐galactosidase A (AGAL‐A) enzyme activity and progressive accumulation of globotriaosylceramide (Gb3) and its deacylated form globotriaosylsphingosine (lysoGb3) in cells throughout the body. FD can be multisystemic with neurological, renal, cutaneous and cardiac involvement or be limited to the heart.Cardiac involvement is characterized by progressive cardiac hypertrophy, fibrosis, arrhythmias, heart failure and sudden cardiac deat...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Position Paper Source Type: research
Heart Failure in Atrial Fibrillation - An Update on Clinical and Echocardiographic Implications. Circ J. 2020 Jul 08;: Authors: Taniguchi N, Miyasaka Y, Suwa Y, Harada S, Nakai E, Shiojima I Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia in adults and has unfavorable consequences such as stroke, heart failure (HF), and death. HF is the most common adverse event following AF and the leading cause of death. Therefore, identifying the association between AF and HF is important to establish risk stratification for HF in AF. Recent studies suggested that left atrial and ventric...
Source: Circulation Journal - Category: Cardiology Authors: Tags: Circ J Source Type: research
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