Conditional Survival After IPAA for Ulcerative and Indeterminate Colitis: Does Long-term Pouch Survival Improve or Worsen With Time?

CONCLUSIONS: Overall conditional pouch survival improved over time for patients with postoperative anastomotic leak and abscess. These novel findings can be useful to counsel patients regarding expectations for long-term pouch survival even if they develop leaks and abscesses. See Video Abstract at http://links.lww.com/DCR/B217. SUPERVIVENCIA CONDICIONAL DESPUÉS DE ANASTOMOSIS CON BOLSA ÍLEO ANAL, PARA COLITIS ULCERATIVA E INDETERMINADA: ¿LA SOBREVIDA DE LA BOLSA A LARGO PLAZO, MEJORA O EMPEORA CON EL TIEMPO? ANTECEDENTES: Los factores de riesgo para la sobrevida de la bolsa, pueden o no tener una relación lineal con la pérdida de la bolsa y con el tiempo. La supervivencia condicional es un método para describir estas relaciones no lineales de tiempo, hasta el evento informando la supervivencia esperada en varios puntos de tiempo. OBJETIVO: El objetivo de este estudio fue calcular la supervivencia condicional de la bolsa, en función de aparición de factores de riesgo para la pérdida de bolsa. DISEÑO: Estudio retrospectivo de una base de datos institucional. AJUSTES: Cleveland Clinic Foundation. PACIENTES: Pacientes con colitis ulcerativa o indeterminada, sometidos a una anastomosis de bolsa íleo anal, de 1986 a 2016. PRINCIPALES MEDIDAS DE RESULTADO: Los pacientes fueron estratificados en función de la fuga anastomótica postoperatoria, absceso o aparición de f&iac...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Inflammatory Bowel Disease Source Type: research

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Publication date: 30 August 2020Source: International Journal of Pharmaceutics, Volume 586Author(s): Qing Tang, Wei Zhang, Chong Zhang, Yang Guan, Jiahui Ding, Caiyan Yuan, Chen Tan, Xueqin Gao, Songwei Tan
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Authors: Castellotti P, Riccardi N, Ferrarese M, Canetti D, Fanti D, Forti E, Reda M, Alexiadis S, Bonoldi E, Saporiti M, Perno CF, Ruffo Codecasa L Abstract Inflammatory Bowel Diseases (IBD) and intestinal tuberculosis (ITB) frequently share similar clinical, radiological, endoscopic and histologic features. The misdiagnosis of IBD can lead to worsening of ITB course, eventually with dissemination of Mycobacterium tuberculosis (MTB) due to immunosuppressive treatment. We herein report a challenging diagnosis of ITB, progressed from localized to disseminated, in a pregnant woman previously misdiagnosed with Crohn' ...
Source: New Microbiologica - Category: Microbiology Tags: New Microbiol Source Type: research
Publication date: Available online 14 July 2020Source: Clinica Chimica ActaAuthor(s): Lisa M. Johnson, Sandra K. White, Robert L. Schmidt
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
AbstractWhile the pathogenesis of Parkinson ’s disease is not fully understood, there is increasing evidence that inflammatory responses in the brain are implicated in both disease initiation and progression. The inflammatory process in Parkinson’s disease is, however, not limited to the brain but also involves the gastrointestinal tract. High amounts of cytokines and inflammatory markers are found in the colon of Parkinson’s disease patients and there is now strong epidemiological and genetical evidence linking Parkinson’s disease to inflammatory bowel diseases. Recent findings obtained in both exp...
Source: Journal of Neurology - Category: Neurology Source Type: research
Inflammatory bowel disease is associated with intestinal dysbiosis and with elevated antibody production toward microbial epitopes. The underlying processes linking the gut microbiota with inflammation are still unclear. Considering the constant induction of antibodies by gut microbial glycans, the aim of this study was to address whether the repertoire of carbohydrate-specific antibodies is altered in Crohn’s disease or ulcerative colitis. IgG and IgM reactivities to oligosaccharides representative of mucosal glycans were tested in blood serum from 20 healthy control subjects, 17 ulcerative colitis patients, and 23 ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This article reviews the pathologic features and clinical significance of esophagitis, gastritis, and duodenitis associated with inflammatory bowel disease.
Source: Surgical Pathology Clinics - Category: Pathology Authors: Source Type: research
The affiliation of the author Silvio Danese has been incorrectly published in the original publication.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
The affiliation of the author Silvio Danese has been incorrectly published in the original publication. The complete correct affiliation should read as follows.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
The affiliation of the author Silvio Danese has been incorrectly published in the original publication.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
Condition:   Crohn Disease Intervention:   Diagnostic Test: abdominal [18F]FDG PET/CT Sponsor:   Central Hospital, Nancy, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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