Depression in girls with obesity and polycystic ovary syndrome and/or type 2 diabetes

Publication date: Available online 6 June 2020Source: Canadian Journal of DiabetesAuthor(s): Jessie Benson, Cameron Severn, Julia Hudnut-Beumler, Stacey L. Simon, Natalie Abramson, Lauren B. Shomaker, Lauren D. Gulley, Anya Taylor, Megan M. Kelsey, Kristen J. Nadeau, Philip Zeitler, Laura Pyle, Melanie Cree-Green
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research

Related Links:

Background: Youth-onset type 2 diabetes (T2D) is increasing in many countries, creating large personal and societal burdens. While many primary health-care professionals (HCPs) are aware of the classic symptoms of T2D, there are several other manifestations that could indicate its presence.Summary: This narrative review summarizes information on these symptoms and indicators, focusing on those less well known. The classic symptoms and comorbidities include frequent urination, excessive thirst, metabolic syndrome, and obesity. In addition to these, the presence of dermatological (e.g., acanthosis nigricans, granuloma annula...
Source: Annals of Nutrition and Metabolism - Category: Nutrition Source Type: research
Maunil K. Desai1 and Roberta Diaz Brinton2,3* 1School of Pharmacy, University of Southern California, Los Angeles, CA, United States 2Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, United States 3Departments of Pharmacology and Neurology, College of Medicine, University of Arizona, Tucson, AZ, United States Women have a higher incidence and prevalence of autoimmune diseases than men, and 85% or more patients of multiple autoimmune diseases are female. Women undergo sweeping endocrinological changes at least twice during their lifetime, puberty and menopause, with many women undergoin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
We examined the effects of the independent and combined effects of Zataria Multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women. Forty-eight postmenopausal women were divided into four groups: Exercise (EG, n = 12), Zataria Multiflora (ZMG, n = 12), exercise and Zataria Multiflora (ZMEG, n = 12), and control (CG, n = 12). Participants in experimental groups either performed CRT (3 sessions per week with intensity at 55% of one-repetition maximum) or supplemented with Zataria Multiflora (500 mg every day after breakfast with 100 ml of water), or their combination...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
We report a fixed-effect, inverse-weighted-variance meta-analysis from 10,074 PCOS cases and 103,164 controls of European ancestry and characterisation of PCOS related traits. We identified 3 novel loci (nearPLGRKT,ZBTB16 and MAPRE1), and provide replication of 11 previously reported loci. Only one locus differed significantly in its association by diagnostic criteria; otherwise the genetic architecture was similar between PCOS diagnosed by self-report and PCOS diagnosed by NIH or non-NIH Rotterdam criteria across common variants at 13 loci. Identified variants were associated with hyperandrogenism, gonadotropin regulation...
Source: PLoS Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
Polycystic ovary syndrome (PCOS) is a complex endocrine condition that represents a lifelong health concern for 1 in 10 women worldwide.1 PCOS is commonly diagnosed by the presence of ovulatory dysfunction, androgen excess, and/or ovaries with polycystic morphology on ultrasound examination.2 Half of patients experience overweight or obesity.3 Most are at increased risk for serious comorbidities, including infertility, pregnancy complications (eg, gestational diabetes mellitus), impaired glucose tolerance, insulin resistance, type 2 diabetes mellitus, cardiovascular disease, gynecological cancers, anxiety, depression, eati...
Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: Research Source Type: research
Authors: Stefanaki C, Pervanidou P, Boschiero D, Chrousos GP Abstract Recent studies have suggested that body composition is key to health and disease. First, fat tissue is a complex, essential, and highly active metabolic and endocrine organ that responds to afferent signals from traditional hormone systems and the central nervous system but also expresses and secretes factors with important endocrine, metabolic, and immune functions. Second, skeletal muscle mass is an important predictor of health in adult life, while severe mass loss has been associated with the frailty of old age. Studies have shown that skelet...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
ConclusionsContrary to results of previous population‐based studies, HS is relatively common, with a UK prevalence of 0.77%, one‐third being unrecognised, criteria‐diagnosed cases using the most stringent disease definition. If probable cases are included, HS prevalence rises to 1.19%.This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
CONCLUSIONS: Contrary to results of previous population-based studies, HS is relatively common, with a UK prevalence of 0.77%, one-third being unrecognised, criteria-diagnosed cases using the most stringent disease definition. If probable cases are included, HS prevalence rises to 1.19%. This article is protected by copyright. All rights reserved. PMID: 29094346 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Polycystic ovary syndrome (PCOS) is the most frequent endocrine disorder in women of reproductive age, affecting 4%-10% of the population. It is a complex disorder classically characterized by chronic oligo- or anovulation, polycystic ovaries, and hyperandrogenism. It is also associated with a number of comorbid conditions, including type 2 diabetes, cardiovascular disease, dyslipidemia, obesity, infertility, and breast and endometrial cancer [1,2]. In addition, psychiatric disorders are observed more often in PCOS patients than in the general population, particularly depressive, anxiety, and eating disorders [3 –6].
Source: Canadian Association of Radiologists Journal - Category: Radiology Authors: Tags: Neuroradiology / Neuroradiologie Source Type: research
In conclusion, strategies for the prevention and amelioration of long-term morbidities in PCOS are presented. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Review Article Source Type: research
More News: Canada Health | Depression | Diabetes | Diabetes Type 2 | Eating Disorders & Weight Management | Endocrinology | Girls | Obesity | Ovaries | Polycystic Ovary Syndrome