Pathologic findings of patients with nonalcoholic fatty liver disease and the impact of concurrent hepatitis B virus infection in Taiwan.
CONCLUSION: Advanced fibrosis in patients with NAFLD was common in the biopsy series, and was related to aging, hypertension, diabetes mellitus and concurrent HBV infection. PMID: 32499209 [PubMed - as supplied by publisher]
AbstractObjectiveTo investigate the associations of systolic blood pressure (SBP) and diastolic blood pressure (DBP) with changes in knee cartilage composition and joint structure over 48 months, using magnetic resonance imaging (MRI) data from the Osteoarthritis Initiative (OAI).Materials and methodsA total of 1126 participants with right knee Kellgren-Lawrence (KL) score 0 –2 at baseline, no history of rheumatoid arthritis, blood pressure measurements at baseline, and cartilage T2 measurements at baseline and 48 months were selected from the OAI. Cartilage composition was assessed using MRI T2 measuremen...
AbstractSummaryAlendronate is effective in preventing second hip fracture in osteoporotic patients. However, no consensus exists on the duration that is effective in preventing a second hip fracture. Our study demonstrated that risk can be reduced when the prescription is ≥ 6 months for the year following the index hip fracture.IntroductionAlendronate is effective in preventing second hip fracture in osteoporotic patients. However, no consensus exists on the accurate medication possession ratio (MPR) that is effective in preventing a second hip fracture. Our objective was to compare the risk of second hip fr...
Publication date: Available online 13 July 2020Source: Pregnancy HypertensionAuthor(s): C. Birdir, L. Fox, L. Droste, M. Frank, J. Fryze, A. Enekwe, A. Köninger, R. Kimmig, B. Schmidt, A. Gellhaus
Probiotics are living microorganisms, which when taken in adequate amount, provide various health benefits by maintaining the balance of bacteria in the intestine. Probiotics are purported to have countless health benefits, some of which include improved digestion, enhanced immunity, prevention of cancer and diabetes. The most common group of probiotics include species of Lactobacillus, Bifidobacterium and Enterococcus. In order to work as an effective probiotic, the microbial strain is expected to exhibit certain desirable characteristics like acid and bile tolerance, antimicrobial activity, adhesion to intestinal epithel...
Conclusion: The detailed research on the patent information presented herein focused on the activity of the compositions containing jackfruit extract and isolated phytochemicals would assist researchers to understand the mechanisms by which the bio-chemicals exert their effect and the overall nutritional benefits. An increase in the number of publications and patents in recent years related to the use of jackfruit for different health conditions clearly emphasizes its therapeutic potential and importance as medicinal food products and cosmetics.
Conclusion: The current study clearly demonstrates that the Momordica charantia aryl and seed extracts have the potential to exert its cytotoxic effect on breast cancer cells by a mechanism involving inhibition of EGFR and EGRF related pathways with the induction of apoptosis. The overall finding demonstrates that this plant, especially seed extract, could be a potential source of new anticancer compounds for possible drug development against cancer.
Conclusion: These data suggest that SE treatment may affect plasma lipid metabolism and chronic inflammation by upregulating phosphorylation of AMPK and ACC in diabetic rat livers.
Conclusions: The findings highlight an enhanced risk of alcohol and substance use among individuals with severe depression and/or anxiety symptoms above what is seen among individuals with less severe symptomatology. In addition, this study shows a unique risk posed by the presence of depression on substance use. This study offers a framework for future studies to examine the causal mechanisms explaining the connection between psychiatric symptoms and alcohol/substance use. PMID: 32657223 [PubMed - as supplied by publisher]
Publication date: Available online 6 July 2020Source: Asian Nursing ResearchAuthor(s): Youngji Kim, Jung Lim Lee, In Sun Jang, Seungmi Park
Publication date: Available online 13 July 2020Source: Journal of the Formosan Medical AssociationAuthor(s): Tsung-Pei Tsou, Wan-Chin Chen, Angela Song-En Huang, Shan-Chwen Chang, Wan-Chin Chen, Angela Song-En Huang, Chia-Ping Su, Tsung-Pei Tsou, Pin-Hui Lee, Pei-Chun Chan, Hao-Hsin Wu, Shih-Tse Huang, Wei-Ju Su, Ying-Shih Su, Hsin-Yi Wei, Meng-Yu Chen, Pei-Yuan Wu, Kung-Chin Wang, Huai-Te Tsai, Hsin-Chun Lee