Progranulin inhibits LPS-induced macrophage M1 polarization via NF- кB and MAPK pathways

Macrophage M1 polarization plays a pivotal role in inflammatory diseases. Progranulin (PGRN) has potential anti-inflammation action, however, the effect of PGRN on macrophage M1 polarization has been poorly st...

Source: BMC Immunology - June 5, 2020 Category: Allergy & Immunology Authors: Lianlian Liu, Hongmei Guo, Aimei Song, Jiahui Huang, Yu Zhang, Shanshan Jin, Shutong Li, Liguo Zhang, Chengzhe Yang and Pishan Yang Tags: Research article Source Type: research