miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in ischemic stroke.

In conclusion, our work suggests that, in mice, miR-137 confers neuroprotective effects against ischemic stroke via attenuation of oxidative, apoptotic, and inflammatory pathways through inhibiting Src-dependent MAPK signaling pathway. PMID: 32496209 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32496209?dopt=Abstract

Source: Aging - June 3, 2020 Category: Biomedical Science Authors: Tian R, Wu B, Fu C, Guo K Tags: Aging (Albany NY) Source Type: research