Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes.

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB01052A, PaperDale C Guenther, Raymond Emehiser, Allison Inskeep, Saswata Karmakar, Patrick J. Hrdlicka Invader probes, i.e., DNA duplexes modified with +1 interstrand zippers of intercalator-functionalized nucleotides like 2'-O-(pyren-1-yl)methyl-RNA monomers, are energetically activated for sequence-unrestricted recognition of double-stranded DNA (dsDNA) as they are engineered... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - June 5, 2020 Category: Molecular Biology Authors: Dale C Guenther Source Type: research