3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism

Publication date: Available online 4 June 2020Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Alzbeta Stefela, Miroslav Kaspar, Martin Drastik, Ondrej Holas, Milos Hroch, Tomas Smutny, Josef Skoda, Miriama Hutníková, Amit V. Pandey, Stanislav Micuda, Eva Kudova, Petr Pavek
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research