Antidiabetic Triple Therapy Effects on Surrogate Tests After Stroke

Conditions:   Diabetes Mellitus;   Stroke Intervention:   Drug: Metformin plus Pioglitazone plus an SGLT2 inhibitor Sponsors:   Chang Gung Memorial Hospital;   National Taiwan University Hospital;   Chiayi Christian Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Condition:   Stroke Intervention:   Device: T-chair Sponsor:   KU Leuven Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Cerebral Cavernous Malformation;   Cavernous Angioma;   Hemorrhagic Microangiopathy Intervention:   Other: observational Sponsors:   University of Chicago;   Mayo Clinic;   University of California, San Francisco;   National Institute of Neurological Disorders and Stroke (NINDS) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Amyotrophic Lateral Sclerosis;   Brainstem Stroke;   Muscular Dystrophies;   Parkinson's Disease and Parkinsonism;   Multiple System Atrophy;   Brain Tumor Adult;   Spinal Cord Injuries;   Locked-in Syndrome Interventions:   Behavioral: BCI-FIT multi-modal access;   Behavioral: BCI-FIT adaptive signal modeling;   Behavioral: BCI-FIT active querying;   Behavioral: BCI-FIT language modeling Sponsor:   Oregon H...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Stroke;   Subluxation, Glenohumeral Intervention:   Device: kinesiotape Sponsors:   Ankara Physical Medicine and Rehabilitation Education and Research Hospital;   Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A guide on restoration and recovery following a period of rapid change along the whole patient pathway; and an implementation guide for adapting acute services during the pandemic.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
CONCLUSION: Physical and mental health functioning declined among symptomatic individuals and those with stroke/TIA history. Thus, frequent monitoring for the early detection of stroke symptoms may be recommended. PMID: 32653213 [PubMed - as supplied by publisher]
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Authors: Baud JM, Stanciu D, Yeung J, Maurizot A, Chabay S, de Malherbe M, Chadenat ML, Bachelet D, Pico F Abstract INTRODUCTION: Carotid atherosclerosis represents 8 to 15% of ischemic strokes in relation to the concept of "vulnerable" plaque. Contrast enhanced ultrasound (CEUS) can detect moving microbubbles within the plaque corresponding to neovessels that constitute "precursors" of vulnerable plaque and intraplaque hemorrhage. CEUS was not studied specifically in acute ischemic strokes. The aim of this study is to analyse the prevalence of CEUS carotid plaque ipsilateral at the ischemic str...
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
AbstractIntracerebral hemorrhage (ICH) is a non-traumatic cerebrovascular disorder with very high morbidity and mortality and regarded as one of the deadliest stroke subtypes. Notably, there is no effective treatment for ICH. Despite an overall increase in preclinical studies, the pathophysiology of ICH is complex and remains enigmatic. To this end, ICH was induced in male CD-1 mice  and the ipsilateral brain tissue was characterized in an unbiased manner using a combination of proteomics and bioinformatics approaches. A total of 4833 proteins were revealed by quantitative proteomic analysis. Of those, 207 proteins ex...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
CONCLUSIONS: D-ER at either a 7.5 mg or 10 mg dose did not significantly increase performance on the 2 MinWT in stroke survivors with gait impairment, although this study was terminated early before full enrollment. (Clinical Trial # NCT02271217). PMID: 32651338 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - Category: Neurology Tags: Restor Neurol Neurosci Source Type: research
DiscussionThe protocol outlines the methods for systematically reviewing and synthesising evidence of screening strategies for type 2 diabetes mellitus and their effect on health outcomes associated with the disease. The potential impact of this systematic review is improved evidence-informed decision-making for policies and practice for screening of type-2 diabetes.Systematic review registrationPROSPERO CRD42020147439
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
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