Age-dependent association of CYP2C19 polymorphisms with clinical outcome of clopidogrel therapy in minor stroke patients with large-artery atherosclerosis

ConclusionsCarriage of the CYP2C19 LOF allele may prevent expected clinical outcome during clopidogrel therapy in young LAA-associated minor stroke patients, whereas not in older patients.

http://link.springer.com/10.1007/s00228-020-02905-0

Source: European Journal of Clinical Pharmacology - June 4, 2020 Category: Drugs & Pharmacology Source Type: research