Hemodynamic Effects of Propofol and Dexmedetomidine in Septic Patients Without Shock

Conclusions and Relevance: A minority of patients with sepsis who received either propofol or dexmedetomidine experienced an event. Patients with sepsis without shock receiving continuous infusions of propofol and dexmedetomidine experienced a negative hemodynamic event at similar frequencies, though the degree of hypotension seen with propofol was greater. The clinical significance of these adverse effects requires cautious use in sepsis and further investigation.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news