Perinatal transmission in Human Immunodeficiency Virus infection: a cross-sectional study from a tertiary care center in North India.

Perinatal transmission in Human Immunodeficiency Virus infection: a cross-sectional study from a tertiary care center in North India. Infez Med. 2020 Jun 01;28(2):227-230 Authors: Kodan P, Gupta N, Ratna S, Ramprasad A, Ranjan S, Nischal N, Soneja M, Wig N Abstract Perinatal transmission of Human Immunodeficiency Virus (HIV) infection is an important mode of transmission in developing countries. The aim of this study was to evaluate the epidemiology of perinatal transmission of HIV infection in pregnant women living with HIV/Acquired Immune Deficiency Syndrome (AIDS). A cross-sectional study was conducted in which HIV positive females who were pregnant at any time between April 2015 and July 2017 were interviewed and their case records analyzed. The collected data were entered and analyzed using Stata v11. Results were expressed as numbers and percentages for categorical variables and as mean and standard deviation (SD) for continuous variables. In all, 51 women were included in the study, 41 of whom had little knowledge concerning the transmission mode of HIV and its prevention. A total of 28 of these females were diagnosed with HIV during their pregnancy (First trimester -4, second trimester -18 and third trimester -6). A total of four babies delivered by these women were diagnosed with HIV. All the four babies were delivered by mothers who were diagnosed with HIV in or after the second trimester of the pregnancy. There is a need to create awareness amo...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research

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CONCLUSIONS: The COMBIND intervention was easily integrated into India's existing PMTCT programme and improved early uptake of two PMTCT components that require self-motivated health-seeking behaviour, thus providing preliminary evidence to support COMBIND as a potentially scalable PMTCT strategy. Further study would identify modifications needed to optimize other PMTCT outcomes. PMID: 32618115 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: Data integration was feasible and identified gaps in programme implementation/documentation leading to corrective interventions. Incident infections among mothers are the largest contributors to MTCT: there is need to strengthen the prevention cascade among HIV-negative women. PMID: 32602644 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: We successfully identified recently acquired infections among persons testing HIV-positive in routine testing settings and highlight the importance of incorporating additional information to accurately classify recent infection. We identified a number of groups with a significantly higher proportion of recent infection, suggesting recent infection surveillance, when rolled-out nationally, may help in further targeting primary prevention efforts. PMID: 32602625 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
This study examined maternal-fetal outcomes in pregnant HIV-positive women who use opioids.Southern Medical Journal
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Family Medicine/Primary Care Journal Article Source Type: news
This study quantifies differentials in HIV care, treatment and mortality outcomes for men and women over time in South Africa. METHODS: We analysed population-wide linked anonymized data, including vital registration linkage, for the Western Cape Province, from the time of first CD4 count. Three antiretroviral therapy guideline eligibility periods were defined: 1 January 2008 to 31 July 2011 (CD4 cell count
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Conclusion: Efavirenz and didanosine exposure during pregnancy were associated with higher risk of neurologic abnormalities in CHEU, and dolutegravir exposure showed some suggestive associations, which warrant further monitoring.
Source: AIDS - Category: Infectious Diseases Tags: EPIDEMIOLOGY AND SOCIAL Source Type: research
Objective(s): We sought to determine whether universal ‘test and treat’ (UTT) can achieve gains in viral suppression beyond universal antiretroviral treatment (ART) eligibility during pregnancy and postpartum, among women living with HIV. Design: A community cluster randomized trial. Methods: The SEARCH UTT trial compared an intervention of annual population testing and universal ART with a control of baseline population testing with ART by country standard, including ART eligibility for all pregnant/postpartum women, in 32 communities in Kenya and Uganda. When testing, women were asked about current pr...
Source: AIDS - Category: Infectious Diseases Tags: EPIDEMIOLOGY AND SOCIAL Source Type: research
Conditions:   Sexually Transmitted Infection;   HIV/AIDS;   Cost-effectiveness;   Birth Outcomes;   Vaginal Microbiome;   Neisseria Gonorrhoeae;   Chlamydia Trachomatis;   Trichomonas Vaginalis;   Antenatal Care;   Pregnancy Interventions:   Diagnostic Test: First antenatal care + test-of-cure;   Diagnostic Test: First antenatal care + week 30-34 gestation (no test-of-cure) Sponsors:   Foundation for Professional Development (Pty) Ltd;   University of California, Los Ang...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Makuei G, Abdollahian M, Marion K Abstract Maternal mortality rate (MMR) is one of the main worldwide public health challenges. Presently, the high levels of MMR are a common problem in the world public health and especially, in developing countries. Half of these maternal deaths occur in Sub-Saharan Africa where little or nothing progress has been made. South Sudan is one of the developing countries which has the highest MMR. Thus, this paper deploys statistical analysis to identify the significant physiological causes of MMR in South Sudan. Prediction models based on Poisson Regression are then developed...
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
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