Assessment of metabolic pattern in betel quid dependence individuals brain using 18F-FDG-PET

Conclusions: In our study, we found that hypermetabolism in the cerebellum and thalamus, and hypometabolism in PFC. We figured out a glucose metabolic pattern of BQD individual’s brain which may be a metabolic pattern with PFC's hypometabolism as the core node. This finding may help us further understanding BQ's unique addiction mechanism, and guide the follow-up of BQ addiction treatment. Acknowledgement: This study was supported by the National Natural Science Foundation of China, Grant No.81801740.Regions showing glucose metabolism differences between BQD and HCRegionMIN XYZClusterT scores of peak voxelRegion location(ALL)Right Cerebellum Posterior Lobe26 ,-38, -4083.78Cerebelum_10_RLeft Cerebellum Anterior Lobe16 ,-38, -18873.88Cerebelum_4_5_LRight Cerebellum Anterior Lobe2 ,-60, -2953.74Vermis_4_5 ,Vermis_6Thalamus14, -6 , 6143.9Thalamus_L,Thalamus_RRight Frontal Lobe46 , 32, 3050-4.27Frontal_Inf_Tri_R,Frontal_Mid_RLeft Frontal Lobe-44 , 20 , 3643-4.03Frontal_Mid_L,Frontal_Inf_Tri_L,Frontal_Inf_Oper_L
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Neurology & amp; Psychiatry (Poster Session) Source Type: research