The effects of monosodium glutamate on PSMA radiotracer uptake in men with recurrent prostate cancer: a prospective, randomized, double-blind, placebo-controlled intra-individual imaging study.

Conclusions: Orally administered MSG significantly decreased salivary gland, kidney and other normal organ PSMA radiotracer uptake in human subjects, using 18F-DCFPyL as an exemplar. However, MSG also caused a corresponding reduction in tumor uptake, which may limit the benefits of this approach for diagnostic and therapeutic applications.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: GU - Radioligand Therapy (Poster Session) Source Type: research