Predicting Gemcitabine Uptake by 18F-FAC in Murine Models of Pancreatic Cancer

Conclusions: PEGPH20 had moderate effects on tumor uptake of gemcitabine. 18F-FAC PET was shown to be a good surrogate for gemcitabine uptake, and when combined with MR, to successfully determine drug uptake in tumors growing in the pancreas.18F-FAC identified PEGPH20-increases in tumor gemcitabine.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Basic Oncology & amp; Translational (Poster Session) Source Type: research