Molecular imaging of inflammation in the brain-heart axis after ischemic stroke: comparison of two murine stroke models.

Conclusions: In contrast to topical ET-1 application after craniotomy, the intravascular MCAo model enables imaging studies of brain-heart networking after stroke, which evokes elevated TSPO PET signal in both brain and heart. The severity of cerebral ischemic damage may contribute to cardiac dysfunction via systemic inflammatory networking.

Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Hermanns, N., Bascunana, P., Langer, B. L. N., Wolf, B., Bankstahl, J., Ross, T., Bengel, F., Thackeray, J. Tags: Cardiovascular Council YIA Symposium Source Type: research