Ocular Dirofilariasis after Clinically Manifested Subcutaneous Migration of the Parasite: A Case Report.
Ocular Dirofilariasis after Clinically Manifested Subcutaneous Migration of the Parasite: A Case Report. Iran J Parasitol. 2020 Jan-Mar;15(1):147-152 Authors: Ondriska F, Boldiš V, Stanislavová M, Antolová D, Miterpáková M, Hanáček A, Vešperová S, Jančovič I Abstract Dirofilaria repens is the causative agent of human subcutaneous or, less often, ocular dirofilariasis. The work presents a rare case of ocular dirofilariasis manifested by previous subcutaneous migration accompanied by severe headache symptoms. In February 2017, a 58-yr-old man from Trnava region, western Slovakia, noticed red and itchy stripes on his left leg. Inflamed but painless stripes disappeared and showed up again every 5-7 days, migrating gradually towards the head. Approximately one month after the first skin's alterations, strong pain in the left temple, with the swelling of the left face and the enlargement of mandibular lymph nodes appeared. Several days later, the patient felt excruciating pain of the right eyeball accompanied by strong nausea and subsequent vomiting. Ocular examination revealed the presence of a live worm in the subconjunctival space and morphological and molecular analyses of extracted helminth confirmed D. repens as etiological agent of the infection. According to clinical manifestation of the infection, it could be supposed that ocular form of the disease was the result of the migration of a parasite...
CONCLUSIONS: AS poses a significant burden for the Spanish National Health System and society. PMID: 32662412 [PubMed - as supplied by publisher]
Authors: Alahdal M, Duan L, Ouyang H, Wang D Abstract Osteoarthritis (OA) is a chronic degenerative joint disease and a leading cause of disability. It involves articular cartilage destruction and a whole joint inflammation. In spite of OA pathogenesis is still unclear, new studies on the OA pathophysiological aetiology and immunomodulation therapy continuously achieve significant advances with new concepts. Here, we focus on the indoleamine-2,3-dioxygenase1 (IDO1) activity in the osteoarthritis (OA), which is one of the noticeable enzymes in the synovial fluid of arthritis patients. It was recognized as an essenti...
Publication date: Available online 15 July 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Jonathan Gonçalves de Oliveira, Tatiana Rozental, Alexandro Guterres, Bernardo Rodrigues Teixeira, Beatriz Elise Andrade-Silva, Sócrates Fraga da CostaNeto, Marina Carvalho Furtado, Ricardo Moratelli, Paulo Sérgio D'Andrea, Elba Regina Sampaio Lemos
Authors: Pain C, Lanius R PMID: 32660939 [PubMed - in process]
Publication date: Available online 15 July 2020Source: Physiology &BehaviorAuthor(s): Kristina Ängeby Möller, Cecilia Aulin, Azar Baharpoor, Camilla I Svensson
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB01215G, PaperWangjian Sheng, Bing Xu, Shaoming Chen, Yuqing Li, Bin Liu, Huan Wang NAI-112 is a glycosylated class III lanthipeptide produced by an Actinoplanes sp. strain with potent bioactivity against nociceptive pain. NAI-112 contains two labionin/methyllabionin motifs and a rare deoxyhexose modification N-linked... The content of this RSS Feed (c) The Royal Society of Chemistry
Publication date: Available online 14 July 2020Source: Journal of PhysiotherapyAuthor(s): Shaiane Silva Tomazoni, Matheus Oliveira Almeida, Jan Magnus Bjordal, Martin Bjørn Stausholm, Caroline dos Santos Monteiro Machado, Ernesto Cesar Pinto Leal-Junior, Leonardo Oliveira Pena Costa
CONCLUSIONS: Our study is the first study to investigate the association between Ala1369Ser ABCC8 genetic variation and T2DM in the Kurdish population of western Iran. The obtained results clearly show that Ala1369Ser polymorphism of ABCC8 is associated with an increased risk of T2DM in this population. PMID: 32660410 [PubMed - as supplied by publisher]
Conclusions: There remains a lack of sound data supporting the effectiveness of antipsychotic treatment for primary DI. Further research is required to establish more definitive conclusions about the relative clinical utility of antipsychotic agents for DI. PMID: 32658556 [PubMed - as supplied by publisher]
Authors: Tanner EA, Gary MA, Davis AA, Michalik S, McFarlin BK Abstract Endurance running training can lead to gradual accumulation of inflammation and soreness ultimately resulting in overuse injuries. Management of soreness and inflammation with pharmaceuticals (i.e. non-prescription pain relievers) during long-term training is not a suitable solution due to known side effects (e.g. gastrointestinal complications, etc.). Dietary polyphenols (i.e. curcumin, pomegranate, etc.) have been purported to reduce inflammation and muscle soreness, without these negative side effects making them ideal for use in an exercise...