Sequences of cognitive decline in typical Alzheimer's disease and posterior cortical atrophy estimated using a novel event-based model of disease progression.

DISCUSSION: Our model recovered realistic, phenotypical progression signatures that may be applied in dementia clinical trials for enrichment, and as a data-driven composite cognitive end-point. PMID: 32489019 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32489019?dopt=Abstract

Source: The Journal of Alzheimers Association - June 4, 2020 Category: Psychiatry Tags: Alzheimers Dement Source Type: research